Single-cell transcriptomic profiling of hyperproliferative keratinocytes in hidradenitis suppurativa
Authors: CM Smith1, B Moran1, A Zabarowski3, M Ryan4,8, J Karman4, RW Dunstan4, KM Smith4, J Musilova5, K Hokamp6, KHG Mills1, M O’Donnell7, WJ Housley4, DC Winter3, B Kirby5, JM Fletcher1,2
1 School of Biochemistry and Immunology, Trinity Biomedical Sciences Institute, Trinity College Dublin, 2 School of Medicine, Trinity Biomedical Sciences Institute, Trinity College Dublin. 3 Department of Surgery, St. Vincent’s University Hospital, Dublin. 4 AbbVie, Immunology Systems Computational Biology, Cambridge Research Center, Cambridge, Massachusetts, USA. 5 Department of Dermatology, St. Vincent’s University Hospital, Dublin.6 Department of Genetics, School of Genetics and Microbiology, Smurfit Institute of Genetics, Trinity College Dublin. 7 St Vincent’s Private Hospital, Dublin. 8 Former AbbVie Employee.
Deceleration in the rate of keratinocyte cancers and pre-cancerous lesions during PD-1 inhibition for advanced melanoma, with recrudescence on discontinuation.
L. Roche, B. Moriarty, A. Fabre, J. Crowne, A. Lally,
St Vincent’s Healthcare Group strategic skin cancer network, St Vincent’s University Hospital.
Gender and immunosuppression impact Merkel Cell Carcinoma(MCC) diagnosis and prognosis. A population based cohort study.
E. Keeling1, E. O’Leary2, S. Deady3, JP. O’Neill4, P. Conlon4, F. Moloney5,
1. Galway University Hospital
2. National Cancer Registry Ireland
3. Beaumont Hospital
4. Mater Misericordiae University Hospital
Non-pigmented lesion clinics: A review of the inter-speciality referral pathway for keratinocyte cancers, introduced to reduce hospital contact hours for patients during the COVID-19 pandemic
C. Drumm, C. Doyle, S. Lynch, C. O’Donnell, C. Lawlor, R. Dolan, A. Lally, B. Moriarty.
Department of Dermatology, St Vincent’s University Hospital, School of Medicine, University College Dublin, Department of Plastic and Reconstructive Surgery, St Vincent’s University Hospital.